Piotr Sliz, PhD
HHMI & Harvard Medical School.

Lecturer, Department of Biological Chemistry and Molecular Biology, Harvard Medical School and Howard Hughes Medical Institute Director, SBGrid.org

During his graduate and post-graduate career Dr Piotr Sliz has been offering his computational expertise to biologists. He received his PhD degree from the University of Toronto, Department of Biochemistry. In 1999 he moved to Harvard and by combining computing resources of structural biology laboratories at Harvard University and Children's Hospital in Boston he established a foundation for SBGrid. In it's current form, the SBGrid manages resources for more then 30 structural biology groups from seven universities and four research hospitals and operates a multi-OS grid supporting the most demanding scientific project in macromolecular electron microscopy, X-ray crystallography and NMR. SBGrid as a unique, discipline focused computational operation efficiently supplements institutionally centered IT. As a bonus to its clients, SBGrid recently integrated Apples' G5s with a majority of the standard structural biology applications and positioned the G5 as a central component of the SBGrid computational grid.

During his tenure at Harvard Dr Sliz has continued research in structural biology. He is often involved in structure determination of macromolecules at lower then 3Å resolution, where experimental data are limited and demands for computations increased. His recent collaboration with Harvard Medical School groups resulted in structures of clathrin coats - vehicles of membrane traffic in human cells at 8Å (Nature, 2004) and a membrane junction complex from the eye lens at 3.1Å (Nature, 2004).


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